Pubblicazioni

Autori:

Carollo, Giacomo; Quinci, Riccardo; Mingolla, Gloria Pompea; Sandri, Angela; Tinazzi, Michele; Antelmi, Elena

Titolo:

Restless Legs Syndrome and Impulsive Decision-Making: Impact of Symptom Severity, Chronotype and Interoception

Anno:

2025

Tipologia prodotto:

Articolo in Rivista

Tipologia ANVUR:

Articolo su rivista

Lingua:

Inglese

Formato:

A Stampa

Referee:

Sì

Nome rivista:

MOVEMENT DISORDERS CLINICAL PRACTICE

ISSN Rivista:

2330-1619

N° Volume:

First published online: 18 March 2025

Intervallo pagine:

1-9

Parole chiave:

alexithymia; chronotype; decision making; interoception; restless legs syndrome

Breve descrizione dei contenuti:

Background: Restless Legs Syndrome (RLS) is a neurological disorder reported to be associated with impulsivity and impairments in interoception and emotional regulation. However, limited research has explored the combined influence of RLS severity, psychological factors, and chronotype on impulsive decision-making and risk-taking behavior in RLS patients. Objectives: To assess impulsive-decision making and its modulation by RLS severity, chronotype, and psychological factors (including interoception, anxiety, alexithymia, and sleep quality) in RLS patients compared to healthy controls (HC). Methods: A case-control study was conducted with 20 RLS patients and 20 age- and sex-matched HC. Participants completed a series of questionnaires measuring interoception, anxiety, alexithymia, sleep quality, and chronotype, followed by a temporal discounting task to assess impulsivity. Statistical analyses included Mann-Whitney U tests, Spearman's rank correlations, and multiple regression analysis. Results: No significant differences in impulsive decision-making were observed between groups. RLS patients exhibited higher levels of depression and alexithymia, along with lower scores on interoceptive awareness compared to HC. However, within the RLS group, greater symptoms' severity, poorer sleep quality, and higher anxiety were positively correlated with increased impulsivity. Regression analysis showed that the MAIA-2-Not Distracting sub-scale was a significant predictor of impulsivity in RLS patients. Conclusions: Interoceptive deficits, particularly difficulties in ignoring bodily sensations, play a central role in impulsive decision-making in RLS patients. These findings highlight the importance of targeting interoception, emotional regulation, and sleep quality in therapeutic interventions for RLS. Further research with larger samples is needed to confirm these relationships.

Pagina Web:

https://doi.org/10.1002/mdc3.70040

Id prodotto:

144736

Handle IRIS:

11562/1157789

ultima modifica:

20 marzo 2025

Citazione bibliografica:

Carollo, Giacomo; Quinci, Riccardo; Mingolla, Gloria Pompea; Sandri, Angela; Tinazzi, Michele; Antelmi, Elena, Restless Legs Syndrome and Impulsive Decision-Making: Impact of Symptom Severity, Chronotype and Interoception «MOVEMENT DISORDERS CLINICAL PRACTICE» , vol. First published online: 18 March 2025 , 2025 , pp. 1-9

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