Pubblicazioni

Autori:

Mattiuzzi, Camilla; Henry, Brandon M; Rizk John, G; Lippi, Giuseppe

Titolo:

Mpox (Monkeypox) diagnostic kits - September 2024

Anno:

2025

Tipologia prodotto:

Articolo in Rivista

Tipologia ANVUR:

Articolo su rivista

Lingua:

Inglese

Formato:

A Stampa

Referee:

Sì

Nome rivista:

DIAGNOSIS

ISSN Rivista:

2194-8011

N° Volume:

12

Numero o Fascicolo:

1

Intervallo pagine:

136-137

Parole chiave:

monkeypox; mpox; diagnosis; laboratory medicine

Breve descrizione dei contenuti:

To better describe the current diagnostic alternatives for diagnosing mpox, a search was conducted on the FIND initiative website, the global alliance for diagnostics. As of September 1, 2024, the FIND website lists 131 mpox diagnostic tests. The majority of 98 (74.8%) tests are based on DNA detection using NAATs, while 18 (13.7%) tests detect mpox antigens, 13 (9.9%) tests detect anti-mpox antibodies, 1 (0.8%) test detects both mpox antigens and anti-mpox antibodies and 1 (0.8%) test detects both mpox DNA and RNA. The kits for detecting mpox antigens or anti-mpox antibodies are predominantly RDT (29/31; 93.5%), with the remainder laboratory-based immunoassays (2/31; 6.5%). Importantly, most of these kits, whether NAATs or immunoassays, do not differentiate between Clades I and II, with only two tests capable of specifically detecting DNA of the more aggressive Clade Ib. Overall, 93 (71.0%) of the mpox tests were classified as "regulatory achieved" and 28 (21.4%) tests as "research use only" (RUO), and only five (3.8%) tests - all NAATs - have reached the validation stage.

Id prodotto:

141031

Handle IRIS:

11562/1136066

ultima modifica:

23 febbraio 2025

Citazione bibliografica:

Mattiuzzi, Camilla; Henry, Brandon M; Rizk John, G; Lippi, Giuseppe, Mpox (Monkeypox) diagnostic kits - September 2024 «DIAGNOSIS» , vol. 12 , n. 1 , 2025 , pp. 136-137

Consulta la scheda completa presente nel repository istituzionale della Ricerca di Ateneo