Pubblicazioni

Autori:

Perrone, Fabiana; Belluomini, Lorenzo; Mazzotta, Marco; Bianconi, Maristella; Di Noia, Vincenzo; Meacci, Fiammetta; Montrone, Michele; Pignataro, Daniele; Prelaj, Arsela; Rinaldi, Silvia; Russano, Marco; Sartori, Giulia; Bironzo, Paolo; Facchinetti, Francesco; Menis, Jessica; Tiseo, Marcello; Galetta, Domenico; Novello, Silvia; Pilotto, Sara

Titolo:

Exploring the role of respiratory microbiome in lung cancer: A systematic review

Anno:

2021

Tipologia prodotto:

Articolo in Rivista

Tipologia ANVUR:

Articolo su rivista

Lingua:

Inglese

Referee:

No

Nome rivista:

Critical Review in Oncology/Hematology

ISSN Rivista:

1040-8428

N° Volume:

164

Intervallo pagine:

103404--

Parole chiave:

Lung cancer; Lung microbiota; Prognosis

Breve descrizione dei contenuti:

Giving the potential contribute in cancer initiation and progression, lung microbiota represents a promising topic in cancer research, although still unexplored. We performed a systematic literature search to identify clinical studies evaluating lung microbiota composition, its correlation with lung cancer patients' clinico-pathological features and prognosis. Of the identified 370 studies, 21 were eligible and included. Although studies were heterogeneous, lung cancer resulted to be enriched in peculiar microbial communities, with differences in composition and diversity according to clinico-pathological parameters. Few studies explored how lung microbiota influences cancer outcome. In light of these findings and borrowing the suggestions coming from gut microbiota, we speculate that respiratory microbiome may influence pathogenesis, progression and outcome of lung cancer. Taking advantage of the experience of chronical lung diseases, prospective studies should be designed to evaluate lung microbiota changes throughout any phase of lung cancer course, particularly with the advent of immunotherapy as pivotal treatment.

Id prodotto:

133967

Handle IRIS:

11562/1094607

ultima modifica:

28 maggio 2023

Citazione bibliografica:

Perrone, Fabiana; Belluomini, Lorenzo; Mazzotta, Marco; Bianconi, Maristella; Di Noia, Vincenzo; Meacci, Fiammetta; Montrone, Michele; Pignataro, Daniele; Prelaj, Arsela; Rinaldi, Silvia; Russano, Marco; Sartori, Giulia; Bironzo, Paolo; Facchinetti, Francesco; Menis, Jessica; Tiseo, Marcello; Galetta, Domenico; Novello, Silvia; Pilotto, Sara, Exploring the role of respiratory microbiome in lung cancer: A systematic review «Critical Review in Oncology/Hematology» , vol. 164 , 2021 , pp. 103404--

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