Pembrolizumab as salvage treatment for T-cell/histiocyte-rich and Epstein-Barr virus-positive large B-cell lymphoma
Anno:
2024
Tipologia prodotto:
Articolo in Rivista
Tipologia ANVUR:
Articolo su rivista
Lingua:
Inglese
Referee:
No
Nome rivista:
British Journal of Haematology
ISSN Rivista:
0007-1048
N° Volume:
205
Numero o Fascicolo:
6
Intervallo pagine:
2523-2526
Parole chiave:
T-cell/histiocyte-rich large B-cell lymphoma
Breve descrizione dei contenuti:
Here, we present the results of a pilot study evaluating the efficacy of the anti-PD-1 drug pembrolizumab in seven patients with TCRLBCL (n = 3) or EBV+ DLBCL, NOS (n = 4). All patients had disease relapsed or were refractory to standard chemo-immunotherapy and had received at least two previous lines (range 2–5). Checkpoint inhibitors may represent a potential therapeutic alternative in subsets of patients who do not benefit most of CAR T-cell therapy.