Pubblicazioni

Autori:

Galeone, Antonella; Annicchiarico, Alessia; Buccoliero, Cinzia; Barile, Barbara; Luciani, Giovanni Battista; Onorati, Francesco; Nicchia, Grazia Paola; Brunetti, Giacomina

Titolo:

Diabetic Cardiomyopathy: Role of Cell Death, Exosomes, Fibrosis and Epicardial Adipose Tissue

Anno:

2024

Tipologia prodotto:

Articolo in Rivista

Tipologia ANVUR:

Articolo su rivista

Lingua:

Inglese

Formato:

Elettronico

Referee:

Sì

Nome rivista:

INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES

ISSN Rivista:

1422-0067

N° Volume:

25

Numero o Fascicolo:

17

Intervallo pagine:

1-14

Parole chiave:

diabetic cardiomyopathy; apoptosis; autophagy; pyroptosis; ferroptosis; fibrosis; exosomes

Breve descrizione dei contenuti:

Diabetic cardiomyopathy (DCM) represents one of the typical complications associated with diabetes. It has been described as anomalies in heart function and structure, with consequent high morbidity and mortality. DCM development can be described by two stages; the first is characterized by left ventricular hypertrophy and diastolic dysfunction, and the second by heart failure (HF) with systolic dysfunction. The proposed mechanisms involve cardiac inflammation, advanced glycation end products (AGEs) and angiotensin II. Furthermore, different studies have focused their attention on cardiomyocyte death through the different mechanisms of programmed cell death, such as apoptosis, autophagy, necrosis, pyroptosis and ferroptosis. Exosome release, adipose epicardial tissue and aquaporins affect DCM development. This review will focus on the description of the mechanisms involved in DCM progression and development.

Id prodotto:

141311

Handle IRIS:

11562/1139447

ultima modifica:

6 ottobre 2024

Citazione bibliografica:

Galeone, Antonella; Annicchiarico, Alessia; Buccoliero, Cinzia; Barile, Barbara; Luciani, Giovanni Battista; Onorati, Francesco; Nicchia, Grazia Paola; Brunetti, Giacomina, Diabetic Cardiomyopathy: Role of Cell Death, Exosomes, Fibrosis and Epicardial Adipose Tissue «INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES» , vol. 25 , n. 17 , 2024 , pp. 1-14

Consulta la scheda completa presente nel repository istituzionale della Ricerca di Ateneo