Publications

Visceral Leishmaniasis Following A+AVD Treatment in a Patient with Classical Hodgkin's Lymphoma: A Case Report and Review of the Literature  (2024)

Authors:
Banegas, Daniela Estefania; Moioli, Alessia; Santoni, Eleonora; Tagliavini, Erica; Quaglia, Francesca Maria; Bernardelli, Andrea; Visco, Carlo
Title:
Visceral Leishmaniasis Following A+AVD Treatment in a Patient with Classical Hodgkin's Lymphoma: A Case Report and Review of the Literature
Year:
2024
Type of item:
Articolo in Rivista
Tipologia ANVUR:
Articolo su rivista
Language:
Inglese
Referee:
No
Name of journal:
JOURNAL OF CLINICAL MEDICINE
ISSN of journal:
2077-0383
N° Volume:
13
Number or Folder:
19
Page numbers:
526-531
Keyword:
A+AVD; Hodgkin’s lymphoma; brentuximab–AVD; splenomegaly; visceral leishmaniasis
Short description of contents:
: We present the case of a 43-year-old Caucasian man who developed visceral leishmaniasis (VL) following treatment with a combination of brentuximab vedotin and doxorubicin, vinblastine, and dacarbazine (A+AVD) for advanced-stage classical Hodgkin's lymphoma (cHL). The patient initially showed a favorable response to the treatment, but shortly after completing six cycles, he experienced recurrent fever, splenomegaly, and severe anemia. Extensive infectious disease evaluations led to a diagnosis of VL, confirmed by PCR testing. The patient was treated with amphotericin B, resulting in full clinical recovery. In addition to presenting this rare case, we conducted a full review of the literature on VL in the context of hematological disorders, including non-Hodgkin's lymphoma, splenic marginal zone lymphoma, and other lymphoproliferative diseases. This review highlights the increasing prevalence of VL in immunocompromised individuals, particularly those undergoing treatments like chemotherapy or immunotherapy, and underscores the importance of considering VL in differential diagnoses when such patients present with persistent fever and splenomegaly.
Product ID:
145939
Handle IRIS:
11562/1162815
Last Modified:
May 23, 2025
Bibliographic citation:
Banegas, Daniela Estefania; Moioli, Alessia; Santoni, Eleonora; Tagliavini, Erica; Quaglia, Francesca Maria; Bernardelli, Andrea; Visco, Carlo, Visceral Leishmaniasis Following A+AVD Treatment in a Patient with Classical Hodgkin's Lymphoma: A Case Report and Review of the Literature «JOURNAL OF CLINICAL MEDICINE» , vol. 13 , n. 192024pp. 526-531

Consulta la scheda completa presente nel repository istituzionale della Ricerca di Ateneo IRIS

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