Publications

Authors:

Favaloro, Emmanuel J; Pasalic, Leonardo; Lippi, Giuseppe

Title:

Oral Anticoagulation Therapy: An Update on Usage and Costs in the Endemic COVID-19 Era

Year:

2025

Type of item:

Articolo in Rivista

Tipologia ANVUR:

Articolo su rivista

Language:

Inglese

Format:

Elettronico

Referee:

Sì

Name of journal:

JOURNAL OF CLINICAL MEDICINE

ISSN of journal:

2077-0383

N° Volume:

14

Number or Folder:

8

Page numbers:

2591-2591

Keyword:

Oral Anticoagulation Therapy; COVID-19; Direct Oral Anticoagulants; Apixaban; Warfarin

Short description of contents:

Background/Objectives: Oral anticoagulant (OA) therapy (OAT) may be prescribed to patients for a variety of reasons, with several agent classes currently available as well as emerging. The classical oral anticoagulants are represented by vitamin K antagonists (VKAs), including warfarin, and the more modern alternatives comprise the direct oral anticoagulants (DOACs). We aimed to assess usage of OAs over time in Australia, especially focusing on the period of the coronavirus disease 2019 (COVID-19) pandemic and its transition to an endemic phase, to assess for any trends. Methods: Using data from the pharmaceutical benefits scheme (PBS), Medicare and other online sites, we specifically assessed for changes in OA prescription and cost patterns over the period 1992–2024, but focusing especially on the period 2020–2024 inclusive. Results: Apixaban is now the most prescribed OA in Australia. Costs of OAT prescriptions have steadily increased over the data capture period, reaching half a billion dollars in 2023. Interestingly, costs have started to fall, seemingly driven by the release of DOAC generics and PBS pricing adjustments. We could identify no clear signals related to COVID-19-related changes in prescription trends, contrary to previous reports in other locations. Conclusions: We provide Australian data on both OA usage as well as costs. Despite an ongoing trend to increasing use of DOACs over VKAs, we could not identify any specific COVID-19-related changes.

Web page:

https://www.mdpi.com/2077-0383/14/8/2591

Product ID:

145019

Handle IRIS:

11562/1159367

Last Modified:

April 29, 2025

Bibliographic citation:

Favaloro, Emmanuel J; Pasalic, Leonardo; Lippi, Giuseppe, Oral Anticoagulation Therapy: An Update on Usage and Costs in the Endemic COVID-19 Era «JOURNAL OF CLINICAL MEDICINE» , vol. 14 , n. 8 , 2025 , pp. 2591-2591

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