Publications

Authors:

Zambolin, Fabio; Laginestra, Fabio Giuseppe; Favaretto, Thomas; Giuriato, Gaia; Ottaviani, Matteo Maria; Schena, Federico; Duro-Ocana, Pablo; Mcphee, Jamie S; Venturelli, Massimo

Title:

Activation of skeletal muscle mechanoreceptors and nociceptors reduces the exercise performance of the contralateral homologous muscles

Year:

2024

Type of item:

Articolo in Rivista

Tipologia ANVUR:

Articolo su rivista

Language:

Inglese

Format:

A Stampa

Referee:

Sì

Name of journal:

AMERICAN JOURNAL OF PHYSIOLOGY. REGULATORY, INTEGRATIVE AND COMPARATIVE PHYSIOLOGY

ISSN of journal:

0363-6119

N° Volume:

327

Number or Folder:

4

Page numbers:

389-399

Keyword:

Exercise Performance; Exercise-Induced Muscle Damage; Fatigue; Muscle Nerve Afferents; Stretching

Short description of contents:

Introduction: Increasing evidence suggests that activation of muscle nerve afferents may inhibit central motor drive, affecting contractile performance of remote exercising muscles. While these effects are well documented for metaboreceptors, very little is known about the activation of mechano- and mechano-nociceptive afferents on performance fatigability. Therefore, the purpose of the present study was to examine the influence of mechanoreceptors and nociceptors on performance fatigability. Methods: Eight healthy young males undertook four randomized experimental sessions on separate occasions in which the experimental knee extensors were: a) resting (CTRL), b) passively stretched (ST), c) resting with DOMS (DOMS), or d) passively stretched with DOMS (DOMS+ST), while the contralateral leg performed an isometric time to task failure (TTF). Changes in maximal voluntary contraction (ΔMVC), potentiated twitch force (ΔQtw,pot) and voluntary muscle activation (ΔVA) were also assessed. Results: TTF was reduced in DOMS+ST (-43%) and ST (‑29%) compared with CTRL. DOMS+ST also showed a greater reduction of VA (-25% vs ‑8%, respectively) and MVCcompared with CTRL (‑28% vs -45%, respectively). RPE was significantly increased at the initial stages (20-40-60%) of the TTF in DOMS+ST compared with all conditions. Conclusion: These findings indicate that activation of mechanosensitive and mechano-nociceptive afferents of a muscle with DOMS reduces TTF of the contralateral homologous exercising limb, in part by reducing VA so accelerating mechanisms of central fatigue.

Web page:

https://doi.org/10.1152/ajpregu.00069.2024

Product ID:

141263

Handle IRIS:

11562/1138966

Last Modified:

December 11, 2024

Bibliographic citation:

Zambolin, Fabio; Laginestra, Fabio Giuseppe; Favaretto, Thomas; Giuriato, Gaia; Ottaviani, Matteo Maria; Schena, Federico; Duro-Ocana, Pablo; Mcphee, Jamie S; Venturelli, Massimo, Activation of skeletal muscle mechanoreceptors and nociceptors reduces the exercise performance of the contralateral homologous muscles «AMERICAN JOURNAL OF PHYSIOLOGY. REGULATORY, INTEGRATIVE AND COMPARATIVE PHYSIOLOGY» , vol. 327 , n. 4 , 2024 , pp. 389-399

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