Publications

Authors:

Plebani, Mario; Nichols, James H; Luppa, Peter B; Greene, Dina; Sciacovelli, Laura; Shaw, Julie; Khan, Adil I; Carraro, Paolo; Freckmann, Guido; Dimech, Wayne; Zaninotto, Martina; Spannagl, Michael; Huggett, Jim; Kost, Gerald J; Trenti, Tommaso; Padoan, Andrea; Thomas, Annette; Banfi, Giuseppe; Lippi, Giuseppe

Title:

Point-of-care testing: state-of-the art and perspectives

Year:

2025

Type of item:

Articolo in Rivista

Tipologia ANVUR:

Articolo su rivista

Language:

Inglese

Format:

A Stampa

Referee:

Sì

Name of journal:

CLINICAL CHEMISTRY AND LABORATORY MEDICINE

ISSN of journal:

1437-4331

N° Volume:

63

Number or Folder:

1

Page numbers:

35-51

Keyword:

advantages, applications, limitation, point-of-care (POCT)

Short description of contents:

Point-of-care testing (POCT) is becoming an increasingly popular way to perform laboratory tests closer to the patient. This option has several recognized advantages, such as accessibility, portability, speed, convenience, ease of use, ever-growing test panels, lower cumulative healthcare costs when used within appropriate clinical pathways, better patient empowerment and engagement, and reduction of certain pre-analytical errors, especially those related to specimen transportation. On the other hand, POCT also poses some limitations and risks, namely the risk of lower accuracy and reliability compared to traditional laboratory tests, quality control and connectivity issues, high dependence on operators (with varying levels of expertise or training), challenges related to patient data management, higher costs per individual test, regulatory and compliance issues such as the need for appropriate validation prior to clinical use (especially for rapid diagnostic tests; RDTs), as well as additional preanalytical sources of error that may remain undetected in this type of testing, which is usually based on whole blood samples (i.e., presence of interfering substances, clotting, hemolysis, etc.). There is no doubt that POCT is a breakthrough innovation in laboratory medicine, but the discussion on its appropriate use requires further debate and initiatives. This collective opinion paper, composed of abstracts of the lectures presented at the two-day expert meeting "Point-Of-Care-Testing: State of the Art and Perspective" (Venice, April 4-5, 2024), aims to provide a thoughtful overview of the state-of-the-art in POCT, its current applications, advantages and potential limitations, as well as some interesting reflections on the future perspectives of this particular field of laboratory medicine.

Web page:

https://www.degruyter.com/document/doi/10.1515/cclm-2024-0675/html

Product ID:

140198

Handle IRIS:

11562/1128886

Last Modified:

December 1, 2024

Bibliographic citation:

Plebani, Mario; Nichols, James H; Luppa, Peter B; Greene, Dina; Sciacovelli, Laura; Shaw, Julie; Khan, Adil I; Carraro, Paolo; Freckmann, Guido; Dimech, Wayne; Zaninotto, Martina; Spannagl, Michael; Huggett, Jim; Kost, Gerald J; Trenti, Tommaso; Padoan, Andrea; Thomas, Annette; Banfi, Giuseppe; Lippi, Giuseppe, Point-of-care testing: state-of-the art and perspectives «CLINICAL CHEMISTRY AND LABORATORY MEDICINE» , vol. 63 , n. 1 , 2025 , pp. 35-51

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