Publications

Authors:

Campagnaro, Tommaso; Poletto, Edoardo; Tarchi, Paola; Rattizzato, Simone; Verlato, Giuseppe; Conci, Simone; Pedrazzani, Corrado; De Manzini, Nicolò; Guglielmi, Alfredo; Ruzzenente, Andrea

Title:

Evaluation of the ACS-NSQIP Surgical Risk Calculator in Patients with Hepatic Metastases from Colorectal Cancer Undergoing Liver Resection

Year:

2023

Type of item:

Articolo in Rivista

Tipologia ANVUR:

Articolo su rivista

Language:

Inglese

Referee:

No

Name of journal:

Journal of Gastrointestinal Surgery

ISSN of journal:

1091-255X

N° Volume:

27

Number or Folder:

10

Page numbers:

2114-2125

Keyword:

ACS-NSQIP; Colorectal cancer; Liver metastases; Liver surgery; Risk calculator.

Short description of contents:

Background: The American College of Surgeons National Surgical Quality Improvement Program surgical risk calculator (ACS-NSQIP SRC) has been designed to predict morbidity and mortality and help stratify surgical patients. This study evaluates the performance of the SRC for patients undergoing surgery for colorectal liver metastases (CRLM). Methods: SRC was retrospectively computed for patients undergoing liver or simultaneous colon and liver surgery for colorectal cancer (CRC) in two high tertiary referral centres from 2011 to 2020. C-statistics and Brier score were calculated as a mean of discrimination and calibration respectively, for both group and for every level of surgeon adjustment score (SAS) for liver resections in case of simultaneous liver-colon surgery. An AUC ≥ 0.7 shows acceptable discrimination; a Brier score next to 0 means the prediction tool has good calibration. Results: Four hundred ten patients were included, 153 underwent simultaneous resection, and 257 underwent liver-only resections. For simultaneous surgery, the ACS-NSQIP SRC showed good calibration and discrimination only for cardiac complication (AUC = 0.720, 0.740, and 0.702 for liver resection unadjusted, SAS-2, and SAS-3 respectively; 0.714 for colon resection; and Brier score = 0.04 in every case). For liver-only surgery, it only showed good calibration for cardiac complications (Brier score = 0.03). The SRC underestimated the incidence of overall complications, pneumonia, cardiac complications, and the length of hospital stay. Conclusions: ACS-NSQIP SRC showed good predicting capabilities only for 1 out of 5 evaluated outcomes; therefore, it is not a reliable tool for patients undergoing liver surgery for CRLM, both in the simultaneous and staged resections.

Note:

Epub 2023 Aug 14

Product ID:

134958

Handle IRIS:

11562/1102128

Last Modified:

February 23, 2024

Bibliographic citation:

Campagnaro, Tommaso; Poletto, Edoardo; Tarchi, Paola; Rattizzato, Simone; Verlato, Giuseppe; Conci, Simone; Pedrazzani, Corrado; De Manzini, Nicolò; Guglielmi, Alfredo; Ruzzenente, Andrea, Evaluation of the ACS-NSQIP Surgical Risk Calculator in Patients with Hepatic Metastases from Colorectal Cancer Undergoing Liver Resection «Journal of Gastrointestinal Surgery» , vol. 27 , n. 10 , 2023 , pp. 2114-2125

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