Publications

Authors:

Mari, Giulio; Santambrogio, Gaia; Crippa, Jacopo; Cirocchi, Roberto; Origi, Matteo; Achilli, Pietro; Ferrari, Giovanni; Megna, Stefano; Desio, Matteo; Cocozza, Eugenio; Maggioni, Dario; Montroni, Isacco; Spinelli, Antonino; Zuliani, Walter; Costanzi, Andrea; Crestale, Sara; Petri, Roberto; Bicelli, Noemi; Pedrazzani, Corrado; Boccolini, Andrea; Taffurelli, Giovanni; Fingerhut, Abe

Title:

5 year oncological outcomes of the HIGHLOW randomized clinical trial

Year:

2023

Type of item:

Articolo in Rivista

Tipologia ANVUR:

Articolo su rivista

Language:

Inglese

Referee:

No

Name of journal:

European Journal of Surgical Oncology

ISSN of journal:

0748-7983

Page numbers:

1-6

Keyword:

Colon surgery; IMA ligation; Oncological outcomes; Rectal cancer surgery

Short description of contents:

The oncological outcomes of low ligation (LL) compared to high ligation (HL) of the inferior mesenteric artery (IMA) during low-anterior rectal resection (LAR) with total mesorectal excision are still debated. The aim of this study is to report the 5 year oncologic outcomes of patients undergoing laparoscopic LAR with either HL vs. LL of the IMA MATERIALS AND METHODS: Between June 2014 and December 2016, patients who underwent elective laparoscopic LAR + TME in 6 Italian non-academic hospitals were randomized to HL or LL of IMA after meeting the inclusion criteria (HighLow trial; ClinicalTrials.gov Identifier NCT02153801). We analyzed the rate of local recurrence, distant metastasis, overall survival, disease-specific survival, and disease-free survival at 5 years of patients previously enrolled.

Note:

Article in press

Product ID:

130572

Handle IRIS:

11562/1078667

Last Modified:

September 28, 2023

Bibliographic citation:

Mari, Giulio; Santambrogio, Gaia; Crippa, Jacopo; Cirocchi, Roberto; Origi, Matteo; Achilli, Pietro; Ferrari, Giovanni; Megna, Stefano; Desio, Matteo; Cocozza, Eugenio; Maggioni, Dario; Montroni, Isacco; Spinelli, Antonino; Zuliani, Walter; Costanzi, Andrea; Crestale, Sara; Petri, Roberto; Bicelli, Noemi; Pedrazzani, Corrado; Boccolini, Andrea; Taffurelli, Giovanni; Fingerhut, Abe, 5 year oncological outcomes of the HIGHLOW randomized clinical trial «European Journal of Surgical Oncology» , 2023 , pp. 1-6

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